Team

  • Ärztliche Leitung

Schwerpunkte

Unsere Arbeitsgruppe betreut und studiert Kinder und Jugendliche mit allen Erkrankungen des Magen-Darm-Traktes und der Leber sowie Patienten mit Ernährungsproblemen. Wir bieten das gesamte Spektrum an notwendiger Diagnostik und Therapie zur Behandlung der entsprechenden Erkrankungen einschließlich endoskopischer Techniken und der Lebertransplantation im Kindesalter an. In unserem Team arbeiten mehrere zertifizierte Kindergastroenterologen und Fachärzte für Kinder- und Jugendmedizin eng mit Spezialisten aus anderen Fachdisziplinen zusammen. Die enge Kooperation mit Kinderchirurgen, Kinderradiologen, Transplantationsmedizinern und Fachkräften für Ernährung und Diätetik gewährleistet eine umfassende Betreuung unserer Patienten in der Kinderklinik des UKE.

Publikationen

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  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2011
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Vor

Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency
Felzen A, van Wessel D, Gonzales E, Thompson R, Jankowska I, Shneider B, Sokal E, Grammatikopoulos T, Kadaristiana A, Jacquemin E, Spraul A, Lipiński P, Czubkowski P, Rock N, Shagrani M, Broering D, Nicastro E, Kelly D, Nebbia G, Arnell H, Fischler B, Hulscher J, Serranti D, Arikan C, Polat E, Debray D, Lacaille F, Goncalves C, Hierro L, Muñoz Bartolo G, Mozer-Glassberg Y, Azaz A, Brecelj J, Dezsőfi A, Calvo P, Grabhorn E, Hartleif S, van der Woerd W, Kamath B, Wang J, Li L, Durmaz Ö, Kerkar N, Jørgensen M, Fischer R, Jimenez-Rivera C, Alam S, Cananzi M, Laverdure N, Ferreira C, Guerrero F, Wang H, Sency V, Kim K, Chen H, de Carvalho E, Fabre A, Bernabeu J, Zellos A, Alonso E, Sokol R, Suchy F, Loomes K, McKiernan P, Rosenthal P, Turmelle Y, Horslen S, Schwarz K, Bezerra J, Wang K, Hansen B, Verkade H
JHEP REP. 2023;5(2):100626.

∆4-3-oxo-5β-reductase deficiency: favorable outcome in 16 patients treated with cholic acid
Gardin A, Ruiz M, Beime J, Cananzi M, Rathert M, Rohmer B, Grabhorn E, Almes M, Logarajah V, Peña-Quintana L, Casswall T, Darmellah-Remil A, Reyes-Domínguez A, Barkaoui E, Hierro L, Baquero-Montoya C, Baumann U, Fischler B, Gonzales E, Davit-Spraul A, Laplanche S, Jacquemin E
ORPHANET J RARE DIS. 2023;18(1):383.

Liver cirrhosis in children - the role of imaging in the diagnostic pathway
Herrmann J, Petit P, Grabhorn E, Lenz A, Jürgens J, Franchi-Abella S
PEDIATR RADIOL. 2023;53(4):714-726.

Mild Crigler-Najjar Syndrome with Progressive Liver Disease-A Multicenter Retrospective Cohort Study
Junge N, Hentschel H, Krebs-Schmitt D, Stalke A, Pfister E, Hartleben B, Claßen M, Querfurt A, Münch V, Bufler P, Oh J, Grabhorn E
CHILDREN-BASEL. 2023;10(9):.

Protocol biopsies in pediatric liver transplantation recipients improve graft histology and personalize immunosuppression
Karbaum E, Weidemann S, Grabhorn E, Fischer L, Herden U, Oh J, Briem-Richter A, Krebs-Schmitt D
J PEDIATR GASTR NUTR. 2023;76(5):627-633.

Long-term outcome after combined or sequential liver and kidney transplantation in children with infantile and juvenile primary hyperoxaluria type 1
Loos S, Kemper M, Schmaeschke K, Herden U, Fischer L, Hoppe B, Levart T, Grabhorn E, Schild R, Oh J, Brinkert F
FRONT PEDIATR. 2023;11:.

Long-term Outcome of Pediatric Liver Transplant Recipients Who Have Reached Adulthood: A Single-center Experience
Lund L, Grabhorn E, Rüther D, Buchholz A, Lang M, Herden U, Fischer L, Sterneck M
TRANSPLANTATION. 2023;107(8):1756-1763.

Cell-based BSEP trans-inhibition: A novel, non-invasive test for diagnosis of antibody-induced BSEP deficiency
Stindt J, Dröge C, Lainka E, Kathemann S, Pfister E, Baumann U, Stalke A, Grabhorn E, Shagrani M, Mozer-Glassberg Y, Hartley J, Wammers M, Klindt C, Philippski P, Liebe R, Herebian D, Mayatepek E, Berg T, Schmidt-Choudhury A, Wiek C, Hanenberg H, Luedde T, Keitel V
JHEP REP. 2023;5(7):100690.

Experience with the mTOR Inhibitor Everolimus in Pediatric Liver Graft Recipients
Wehming M, Krebs-Schmitt D, Briem-Richter A, Hegen B, Brinkert F, Fischer L, Grabhorn E
CHILDREN-BASEL. 2023;10(2):.

Prognosis of Children Undergoing Liver Transplantation: A 30-Year European Study
Baumann U, Karam V, Adam R, Fondevila C, Dhawan A, Sokal E, Jacquemin E, Kelly D, Grabhorn E, Pawlowska J, D'Antiga L, Jara Vega P, Debray D, Polak W, de Ville de Goyet J, Verkade H
PEDIATRICS. 2022;150(4):.

Psychosocial situation, adherence, and utilization of video consultation in young adult long-term pediatric liver transplant recipients during COVID-19 pandemic
Kröncke S, Lund L, Buchholz A, Lang M, Briem-Richter A, Grabhorn E, Sterneck M
PEDIATR TRANSPLANT. 2021;25(8):e14121.

Short- and long-term results of liver transplantation according to age at transplant: a single-center experience of 351 children
Özen J, Beime J, Brinkert F, Fischer L, Herden U, Grabhorn E
TRANSPL INT. 2021;34(7):1251-1260.

Impact of donor-specific antibodies on long-term graft survival with pediatric liver transplantation
Schotters F, Beime J, Briem-Richter A, Binder T, Herden U, Grabhorn E
WORLD J HEPATOL. 2021;13(6):673-685.

Outcome of liver transplantation and prevalence of liver fibrosis in Crigler-Najjar syndrome
Schröder H, Junge N, Herden U, Deutschmann A, Weidemann S, Krebs-Schmitt D, Grabhorn E
CLIN TRANSPLANT. 2021;35(4):.

Presence of donor specific HLA class 2 antibodies (DSA class 2) is associated with development of graft fibrosis more than 10 years after liver transplantation-a retrospective single center study
Sultani B, Marget M, Briem-Richter A, Herrmann J, Meisner S, Grabhorn E, Ozga A, Weidemann S, Herden U, Fischer L, Sterneck M
CLIN TRANSPLANT. 2021;35(7):.

Infantile Hepatic Hemangioma: Avoiding Unnecessary Invasive Procedures
Ernst L, Grabhorn E, Brinkert F, Reinshagen K, Königs I, Trah J
PEDIATR GASTROENTERO. 2020;23(1):72-78.

Oxalate retinopathy is irreversible despite early combined liver-kidney transplantation in primary hyperoxaluria type 1
Atiskova Y, Dulz S, Schmäschke K, Oh J, Grabhorn E, Kemper M, Brinkert F
AM J TRANSPLANT. 2019;19(12):3328-3334.

Impact on the hepatic flow velocity after pediatric combined liver-kidney transplantation compared to isolated pediatric liver transplantation-A matched-pair analysis
Hellenkemper J, Grabhorn E, Brinkert F, Lenhartz H, Herrmann J, Fischer L, Helmke K, Herden U
CLIN TRANSPLANT. 2019;33(10):e13687.

Fatigue in pediatric liver transplant recipients and its impact on their quality of life
Petersen I, Noelle J, Buchholz A, Kroencke S, Daseking M, Grabhorn E
PEDIATR TRANSPLANT. 2019;23(1):e13331.

Allogeneic haematopoietic stem cell transplantation eliminates alloreactive inhibitory antibodies after liver transplantation for bile salt export pump deficiency
Brinkert F, Pukite I, Krebs-Schmitt D, Briem-Richter A, Stindt J, Häussinger D, Keitel V, Müller I, Grabhorn E
J HEPATOL. 2018;69(4):961-965.

Hypereosinophilic Syndrome After Liver Transplantation: A Case Report and a Review of the Literature
Aulbert W, Kobbe R, Breuer C, Briem-Richter A, Schäfer H, Brinkert F, Dettmar A, Kemper M, Grabhorn E
TRANSPLANTATION. 2017;101(5):e166-e169.

Sequencing of FIC1, BSEP and MDR3 in a large cohort of patients with cholestasis revealed a high number of different genetic variants
Dröge C, Bonus M, Baumann U, Klindt C, Lainka E, Kathemann S, Brinkert F, Grabhorn E, Pfister E, Wenning D, Fichtner A, Gotthardt D, Weiss K, McKiernan P, Puri R, Verma I, Kluge S, Gohlke H, Schmitt L, Kubitz R, Häussinger D, Keitel V
J HEPATOL. 2017;67(6):1253-1264.

The first case of domino-split-liver transplantation in maple syrup urine disease
Herden U, Li J, Fischer L, Brinkert F, Blohm M, Santer R, Nashan B, Grabhorn E
PEDIATR TRANSPLANT. 2017;21(6):.

Liver transplantation as a potentially lifesaving measure in neuroblastoma stage 4S
Holsten T, Schuster T, Grabhorn E, Hero B, Frühwald M
PEDIATR HEMAT ONCOL. 2017;34(1):17-23.

Hepatic shear wave elastography in children under free-breathing and breath-hold conditions
Jung C, Groth M, Petersen K, Hammel A, Brinkert F, Grabhorn E, Weidemann S, Busch J, Adam G, Herrmann J
EUR RADIOL. 2017;27(12):5337-5343.

Health-related quality of life after combined liver and kidney transplantation in children
Schmaeschke K, Lezius S, Grabhorn E, Kemper M, Brinkert F
PEDIATR TRANSPLANT. 2017;21(4):e12902.

Two Cases of Hepatosplenic T-Cell Lymphoma in Adolescents Treated for Autoimmune Hepatitis
Brinkert F, Arrenberg P, Krech T, Grabhorn E, Lohse A, Schramm C
PEDIATRICS. 2016;138(3):e20154245.

Bile salt export pump-reactive antibodies form a polyclonal, multi-inhibitory response in antibody-induced bile salt export pump deficiency
Stindt J, Kluge S, Dröge C, Keitel V, Stross C, Baumann U, Brinkert F, Dhawan A, Engelmann G, Ganschow R, Gerner P, Grabhorn E, Knisely A, Noli K, Pukite I, Shepherd R, Ueno T, Schmitt L, Wiek C, Hanenberg H, Häussinger D, Kubitz R
HEPATOLOGY. 2016;63(2):524-37.

Forensische Pädopathologie: Akzidentelle Vergiftung durch Inhalation und Exposition gegenüber CO-haltigem Shisha-Rauch.
Dietz E, Kappus S, Ulrich M, Grabhorn E, Püschel K
päd Praktische Pädiatrie. 2015;21(5):288-291.

Long-Term Clinical Relevance of De Novo Donor-Specific Antibodies After Pediatric Liver Transplantation
Grabhorn E, Binder T, Obrecht D, Brinkert F, Lehnhardt A, Herden U, Peine S, Nashan B, Ganschow R, Briem-Richter A
TRANSPLANTATION. 2015;99(9):1876-1881.

Long-term outcomes after liver transplantation for deoxyguanosine kinase deficiency: a single-center experience and a review of the literature
Grabhorn E, Tsiakas K, Herden U, Fischer L, Freisinger P, Marquardt T, Ganschow R, Briem-Richter A, Santer R
LIVER TRANSPLANT. 2014;20(4):464-72.

Outcome of liver re-transplantation in children-Impact and special analysis of early re-transplantation
Herden U, Ganschow R, Grabhorn E, Briem-Richter A, Nashan B, Fischer L
PEDIATR TRANSPLANT. 2014;18(4):377-84.

Developments in pediatric liver transplantation since implementation of the new allocation rules in Eurotransplant
Herden U, Grabhorn E, Briem-Richter A, Ganschow R, Nashan B, Fischer L
CLIN TRANSPLANT. 2014;28(9):1061-8.

Family strain and its relation to psychosocial dysfunction in children and adolescents after liver transplantation
Kaller T, Petersen I, Petermann F, Fischer L, Grabhorn E, Schulz K
PEDIATR TRANSPLANT. 2014;18(8):851-9.

Quantification of prenatal liver and spleen iron in a sheep model and assessment of iron stores in a human neonate with neonatal hemochromatosis using R2* mapping
Schoennagel B, Remus C, Wedegärtner U, Salzmann I, Grabhorn E, Adam G, Fischer R, Harmatz P, Kooijman H, Yamamura J
MAGN RESON MED. 2014;13(3):167-173.

Liver allograft pathology in healthy pediatric liver transplant recipients
Briem-Richter A, Ganschow R, Sornsakrin M, Brinkert F, Schirmer J, Schäfer H, Grabhorn E
PEDIATR TRANSPLANT. 2013;17(6):543-9.

Cytokine concentrations and regulatory T cells in living donor and deceased donor liver transplant recipients
Briem-Richter A, Leuschner A, Haag F, Grabhorn E, Ganschow R
PEDIATR TRANSPLANT. 2013;17(2):185-90.

Peripheral blood biomarkers for the characterization of alloimmune reactivity after pediatric liver transplantation
Briem-Richter A, Leuschner A, Krieger T, Grabhorn E, Fischer L, Nashan B, Haag F, Ganschow R
PEDIATR TRANSPLANT. 2013;17(8):757-64.

Successful outcome of severe Amanita phalloides poisoning in children
Grabhorn E, Nielsen D, Hillebrand G, Brinkert F, Herden U, Fischer L, Ganschow R
PEDIATR TRANSPLANT. 2013;17(6):550-5.

A formula to calculate the standard liver volume in children and its application in pediatric liver transplantation
Herden U, Wischhusen F, Heinemann A, Ganschow R, Grabhorn E, Vettorazzi E, Nashan B, Fischer L
TRANSPL INT. 2013;26(12):1217-24.

Surgical aspects and outcome of combined liver and kidney transplantation in children.
Herden U, Kemper M, Ganschow R, Klaassen I, Grabhorn E, Brinkert F, Nashan B, Fischer L
TRANSPL INT. 2011;24(8):805-811.

Hemorrhagic necrotizing pancreatitis with a huge pseudocyst in a child with Crohn's disease.
Briem-Richter A, Grabhorn E, Wenke K, Ganschow R
EUR J GASTROEN HEPAT. 2010;22(2):234-236.

Effectiveness of Rex shunt in children with portal hypertension following liver transplantation or with primary portal hypertension.
Krebs-Schmitt D, Briem-Richter A, Grabhorn E, Burdelski M, Helmke K, Broering D, Ganschow R
PEDIATR TRANSPLANT. 2009.

Analysis of the CC chemokine receptor 5Delta32 polymorphism in pediatric liver transplant recipients.
Fischer-Maas L, Schneppenheim R, Oyen F, Grabhorn E, Briem-Richter A, Fischer L, Ganschow R
PEDIATR TRANSPLANT. 2008;12(7):769-772.

Emergency liver transplantation in neonates with acute liver failure: long-term follow-up.
Grabhorn E, Briem-Richter A, Fischer L, Ganschow R
TRANSPLANTATION. 2008;86(7):932-936.

Neonates with severe infantile hepatic hemangioendothelioma: limitations of liver transplantation.
Grabhorn E, Briem-Richter A, Fischer L, Krebs-Schmitt D, Ganschow R
PEDIATR TRANSPLANT. 2008.

Liver transplantation for fulminant hepatic failure in infancy: A single center experience.
Strauss A, Grabhorn E, Sornsakrin M, Briem-Richter A, Fischer L, Nashan B, Ganschow R
PEDIATR TRANSPLANT. 2008.

Clinical relevance of autoantibodies after pediatric liver transplantation.
Briem-Richter A, Grabhorn E, Helmke K, Manns M, Ganschow R, Burdelski M
CLIN TRANSPLANT. 2007;21(3):427-432.

Liver transplantation in children with progressive familial intrahepatic cholestasis.
Englert C, Grabhorn E, Briem-Richter A, Rogiers X, Burdelski M, Ganschow R
TRANSPLANTATION. 2007;84(10):1361-1363.

Liver transplantation in children with Alagille syndrome: indications and outcome.
Englert C, Grabhorn E, Burdelski M, Ganschow R
PEDIATR TRANSPLANT. 2006;10(2):154-158.

Tacrolimus-induced cholestatic syndrome following pediatric liver transplantation and steroid-resistant graft rejection.
Ganschow R, Albani J, Grabhorn E, Briem-Richter A, Burdelski M
PEDIATR TRANSPLANT. 2006;10(2):220-224.

Neonatal hemochromatosis: long-term experience with favorable outcome.
Grabhorn E, Briem-Richter A, Burdelski M, Rogiers X, Ganschow R
PEDIATRICS. 2006;118(5):2060-2065.

Long-term evaluation of cyclosporine and tacrolimus based immunosuppression in pediatric liver transplantation.
Hasenbein W, Albani J, Englert C, Spehr A, Grabhorn E, Kemper M, Burdelski M, Ganschow R
PEDIATR TRANSPLANT. 2006;10(8):938-942.

Hypogammaglobulinemia in pediatric liver transplant recipients.
Ganschow R, Englert C, Grabhorn E, Briem-Richter A, Hinrichs B, Broering D, Rogiers X, Burdelski M
PEDIATR TRANSPLANT. 2005;9(2):215-219.

Long-term results of basiliximab induction immunosuppression in pediatric liver transplant recipients.
Ganschow R, Grabhorn E, Schulz A, Alexander V, Rogiers X, Burdelski M
PEDIATR TRANSPLANT. 2005;9(6):741-745.

Hepatoblastoma in a child with progressive familial intrahepatic cholestasis.
Richter A, Grabhorn E, Briem-Richter A, Schaefer H, Burdelski M, Ganschow R
PEDIATR TRANSPLANT. 2005;9(6):805-808.

C2 blood concentrations of orally administered cyclosporine in pediatric liver graft recipients with a body weight below 10 kg
Ganschow R, Richter A, Grabhorn E, Schulz A, von Hugo A, Mir T, Broering D, Rogiers X, Hinrichs B, Burdelski M
PEDIATR TRANSPLANT. 2004;8(2):185-188.

Short- and long-term results of liver transplantation in infants aged less than 6 months.
Grabhorn E, Schulz A, Helmke K, Hinrichs B, Rogiers X, Broering D, Burdelski M, Ganschow R
TRANSPLANTATION. 2004;78(2):235-241.

Basiliximab monotherapy following B-cell lymphoma after pediatric liver transplantation and anti-CD20 therapy.
Venzke A, Ganschow R, Grabhorn E, Rogiers X, Burdelski M
PEDIATR TRANSPLANT. 2003;7(5):404-407.

Cardiac failure in an infant with Chediak-Higashi syndrome: a hypothesis of the effect of diadenosine polyphosphates.
Ganschow R, Grabhorn E, Lemke J, Lepler R
PEDIAT ALLERG IMM-UK. 2002;13(4):307-310.

Liver transplantation in infants: how much immunosuppression is needed?
Ganschow R, Venzke A, Grabhorn E, Broering D, Rogiers X, Burdelski M
TRANSPL P. 2002;34(5):1963.

Liver transplantation in infants younger than 6 months old.
Grabhorn E, Ganschow R, Helmke K, Rogiers X, Burdelski M
TRANSPL P. 2002;34(5):1964-1965.

Saliva IgM and IgA are a sensitive indicator of the humoral immune response to Escherichia coli O157 lipopolysaccharide in children with enteropathic hemolytic uremic syndrome.
Ludwig K, Grabhorn E, Bitzan M, Bobrowski C, Kemper M, Sobottka I, Laufs R, Karch H, Müller-Wiefel D
PEDIATR RES. 2002;52(2):307-313.

Basiliximab in paediatric liver-transplant recipients.
Ganschow R, Grabhorn E, Burdelski M
LANCET. 2001;357(9253):388.

Liver transplantation in children with Alagille syndrome.
Ganschow R, Grabhorn E, Helmke K, Rogiers X, Burdelski M
TRANSPL P. 2001;33(7-8):3608-3609.

Experience with basiliximab in pediatric liver graft recipients.
Ganschow R, Lyons M, Grabhorn E, Venzke A, Broering D, Rogiers X, Hellwege H, Burdelski M
TRANSPL P. 2001;33(7-8):3606-3607.

Letzte Aktualisierung aus dem FIS: 02.12.2024 - 23:32 Uhr